Charles River has over 25 years of experience performing rodent and livestock metabolism studies for compound support and development. We also have expertise in the development of agrochemicals for veterinary applications, such as ectoparasiticides.
Our scientists offer a comprehensive and integrated service for the profiling and identification of metabolites in excreta, milk, eggs, and tissues. Modern chromatographic and isolation technologies are supported by QToF and IT-ToF mass spectrometers, as well as access to NMR for definitive metabolite identification. Our synthetic chemistry group can provide metabolite reference standards for future structural confirmation.
From procurement of radiolabelled test items through to submission of the dossier, Charles River has the expertise to ensure a smooth and trouble-free passage through the regulatory process.