Charles River has over 40 years of experience in the many different types of ADME, pharmacokinetic, bioequivalence, residue depletion and target animal safety studies for compliance with EU, VICH, US and Japanese regulations. We work with all common livestock species and all routes of administration, and we have a diverse experience in formulating doses, ranging from aquatic-based solutions to oil-based suspensions. Our modern facilities offer a very large capacity with housing for over 200 lactating cattle.
Species
- Cattle
- Sheep
- Goats
- Pigs (including neonatal)
- Poultry
Routes of Administration
- Topical and dermal
- Oral (dietary, capsule or gavage)
- Intravenous
- Intraperitoneal
- Intramuscular
- Subcutaneous
- Intramammary
- Intratracheal
We offer an integrated analytical service for residue analysis and metabolite profiling and identification.
Tolerance Testing in Target Animals
Experts within our Animal Health Product Development group can design tolerance studies in target animals to meet specific requirements for regulatory submissions. Flexibility in protocols allows us to pay special attention to the in-life use of the product with careful selection of dose levels and animal group sizes.
For more information about our target animal safety testing services, contact us at 1.877.CRIVER.1 or askcharlesriver@crl.com.