chemicals 

Charles River is proud to be supporting the ILSI-BioMed 2012 Conference in Tel Aviv. We will be represented by delegates from our Discovery and Preclinical Services Divisions, as well as Research Models and Services. Visit us at booth 29, or via the conference networking facility, to discuss how our expanding portfolio of services can support your development program from discovery through market approval.

There are several guidance documents which highlight the assays needed to measure immunosuppression, however guidelines for monitoring immunostimulation are lacking. The presentations will focus on assays used to measure immunostimulation for biologics, biosimilars and vaccines. With emphasis on immunogenicity testing, Elispot and cytokine assessments. The presentations will also review how we conduct these safety (toxicity) studies, what makes reproduction and developmental safety (toxicity) study designs unique and different from general safety (toxicity) studies. Why we need to address the issues of male and female fertility, pregnancy, development of offspring for molecules and vaccines that intended for life threatening diseases and when are expected to conduct these evaluations.

This intensive seminar is designed to provide an overview on the basics of LAL test technology with in-depth analysis on the types of test methodology available. In particular, this seminar will focus on problems sometimes encountered in endotoxin testing, including resolving interference issues. The speakers will be available to answer any of your endotoxin testing-related questions.