Our validated lipopolysaccharide (LPS) model is easily modified to address client-specified study needs. For our initial validation study, each mouse receives a LPS injection. At specified time points post-LPS challenge, animals are euthanized and blood collected for cytokine analysis. Animals in the validation experiment below were euthanized at 0.5, 1, 2, 4 and 8 hrs post-LPS challenge. Client studies would compare treated groups against control animals.
Chart of Plasma G-CSF, IL-6 and TNF Response to LPS Challenge in Mice
LPS-Induced Cytokine Release
For more information about our LPS-Induced Cytokine Release model, please contact us at 1.877.CRIVER.1 or firstname.lastname@example.org.