Genetic Testing Services for Research Animal Models | Charles River

copy number determination 

Quantitative PCR (QPCR) Assay: QPCR is used to determine transgene copy number in transgenic animals. 

Fully defining your genetically engineered models is an important part of research. Through the use of quantitative PCR (QPCR), we can assist you with the characterization process by determining transgene copy number. Transgenes typically insert randomly in the genome in multiple tandem copies at a single site, but the site of insertion and number of copies varies in each founder line. Since the number of transgene copies may affect expression of the transgene, determining relative copy numbers for different founders can help in characterizing the transgenic model.

To further characterize your model, Charles River also offers a full-service pathology laboratory. The services offered by this lab can provide you with additional data about your valuable genetically engineered model.

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For more information please call:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

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When you're ready to submit samples for testing, complete this form and email it to gts@crl.com.
Want to know how much your testing program will cost? Fill out this form and someone will be in touch shortly with a quote.
Detailed information about our pathology capabilities.

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