Cutting-edge Preclinical QT Assessment Reduces Late-stage Drug Failures Mar 26, 2013 The clinical effects of drugs on cardiac repolarization and rhythm, particularly the induction of potentially fatal arrhythmias have been increasingly documented over the past two decades. Jacketed External Telemetry: “Covering” Cardiovascular Safety in Repeat-Dose Studies Mar 18, 2013 Jacketed external telemetry (JET) is the latest technology available for collection of continuous electrocardiograms (ECGs) from unrestrained animals. Cardiovascular Safety In Vitro Models Mar 12, 2013 Many drugs have either been withdrawn from the market or placed on restricted use due to their (or their metabolites) undesirable ‘off-target’ effects on the heart. The Evolving Regulatory Perspective of Cardiovascular Risk Assessment Mar 04, 2013 The harmonization of regulatory guidance for drug development traces its origins to the European Community (EC) in the mid 1980’s.
Cutting-edge Preclinical QT Assessment Reduces Late-stage Drug Failures Mar 26, 2013 The clinical effects of drugs on cardiac repolarization and rhythm, particularly the induction of potentially fatal arrhythmias have been increasingly documented over the past two decades.
Jacketed External Telemetry: “Covering” Cardiovascular Safety in Repeat-Dose Studies Mar 18, 2013 Jacketed external telemetry (JET) is the latest technology available for collection of continuous electrocardiograms (ECGs) from unrestrained animals.
Cardiovascular Safety In Vitro Models Mar 12, 2013 Many drugs have either been withdrawn from the market or placed on restricted use due to their (or their metabolites) undesirable ‘off-target’ effects on the heart.
The Evolving Regulatory Perspective of Cardiovascular Risk Assessment Mar 04, 2013 The harmonization of regulatory guidance for drug development traces its origins to the European Community (EC) in the mid 1980’s.
