Blog Type 2 Diabetes Treatments and Potential Effects on Bone May 21, 2013 This post will focus on the currently available treatments for Diabetes along with new therapeutic targets and their potential for effects on bone. Diabetes and the Skeleton: A Sweeter Look to the Future May 13, 2013 Chronic hyperglycemia due to either insulin deficiency or insulin resistance is associated with multiple end organ complications. Less often recognized is the long term effect of high glucose on the skeleton. Diabetic Bones? Amazing Insights into the Relationship Between Diabetes and Bone May 08, 2013 The hypothesis that bone is an important player in the regulation of energy metabolism has emerged over the last decade. Reduction Apr 23, 2013 It Sounds like a Great Idea, but how do we Apply “Reduction” to Toxicology Studies? Listening to Animals Apr 16, 2013 What animals say, and tailoring 3R efforts around it. A Look at the 3Rs Apr 01, 2013 Replacement, Reduction and Refinement–past and present Cutting-edge Preclinical QT Assessment Reduces Late-stage Drug Failures Mar 26, 2013 The clinical effects of drugs on cardiac repolarization and rhythm, particularly the induction of potentially fatal arrhythmias have been increasingly documented over the past two decades. Jacketed External Telemetry: “Covering” Cardiovascular Safety in Repeat-Dose Studies Mar 18, 2013 Jacketed external telemetry (JET) is the latest technology available for collection of continuous electrocardiograms (ECGs) from unrestrained animals. Cardiovascular Safety In Vitro Models Mar 12, 2013 Many drugs have either been withdrawn from the market or placed on restricted use due to their (or their metabolites) undesirable ‘off-target’ effects on the heart. The Evolving Regulatory Perspective of Cardiovascular Risk Assessment Mar 04, 2013 The harmonization of regulatory guidance for drug development traces its origins to the European Community (EC) in the mid 1980’s. Displaying results 21-30 (of 91) |< < 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - 10 > >|
Type 2 Diabetes Treatments and Potential Effects on Bone May 21, 2013 This post will focus on the currently available treatments for Diabetes along with new therapeutic targets and their potential for effects on bone.
Diabetes and the Skeleton: A Sweeter Look to the Future May 13, 2013 Chronic hyperglycemia due to either insulin deficiency or insulin resistance is associated with multiple end organ complications. Less often recognized is the long term effect of high glucose on the skeleton.
Diabetic Bones? Amazing Insights into the Relationship Between Diabetes and Bone May 08, 2013 The hypothesis that bone is an important player in the regulation of energy metabolism has emerged over the last decade.
Reduction Apr 23, 2013 It Sounds like a Great Idea, but how do we Apply “Reduction” to Toxicology Studies?
Cutting-edge Preclinical QT Assessment Reduces Late-stage Drug Failures Mar 26, 2013 The clinical effects of drugs on cardiac repolarization and rhythm, particularly the induction of potentially fatal arrhythmias have been increasingly documented over the past two decades.
Jacketed External Telemetry: “Covering” Cardiovascular Safety in Repeat-Dose Studies Mar 18, 2013 Jacketed external telemetry (JET) is the latest technology available for collection of continuous electrocardiograms (ECGs) from unrestrained animals.
Cardiovascular Safety In Vitro Models Mar 12, 2013 Many drugs have either been withdrawn from the market or placed on restricted use due to their (or their metabolites) undesirable ‘off-target’ effects on the heart.
The Evolving Regulatory Perspective of Cardiovascular Risk Assessment Mar 04, 2013 The harmonization of regulatory guidance for drug development traces its origins to the European Community (EC) in the mid 1980’s.
