Featured Stories

Telemetry in Rodent Models of CNS Disease

04/04/2014

In order to better understand rodent CNS disease models and the effects of drug therapy, there is a need for continuous monitoring of animals upon therapy or safety challenges. Charles River now offers telemetric recording with the use of single or multiple biopotential measurements in mice and rats for CNS drug discovery.

Expanded Large Molecule Bioanalytical Services

04/02/2014

Our Horsham, PA site now offers on-site capabilities for GLP- compliant quantitation of large molecule biotechnology products. By leveraging the immunochemistry expertise at our Nevada and Montreal sites, our Horsham site now also streamlines our safety testing processes, providing you with improved reporting efficiencies as well as support for clinical trials.

Zebrafish: A Powerful Alternative Model for Developmental Toxicity Testing

03/31/2014

Development toxicity testing is typically conducted in rodents, rabbits or other mammalian models. However, recent efforts to develop reliable, fast alternative models to screen compounds have produced several useful methods. Among these, a zebrafish developmental toxicity assay offers a vertebrate model of the entire embryonic period of development. 

Acquisition Enhances Discovery Services

03/31/2014

The acquisition of Argenta and BioFocus uniquely positions Charles River as an early-stage contract research organization with integrated in vitro and in vivo capabilities from target identification and validation through preclinical development.

Assays for CNS Target Engagement in Preclinical Rodent Models

02/26/2014

Dissemination of CNS compound effects for their interaction with the molecular target is an important step for decision making when selecting the lead compound. In addition to CNS efficacy studies, we also offer multiple tools to assess target engagement. 

Reduce Your Risk with Biologics Testing Solutions

02/11/2014

Announcing Biologics Testing Solutions, our comprehensive portfolio of testing for biologics development and manufacturing. Placing your biologics testing study with Charles River reduces your risk of unexpected results and will make you  feel like your sample never left your hands. 

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