02/07/2013
To date, approximately 60 KO mouse lines have been sent to Charles River for expansion, and cohorts for 5 KO lines have entered the comprehensive phenotyping platform.
02/04/2013
Charles River is pleased to announce the addition of physicochemical testing services to the portfolio at our Ohio facility. Until now, physicochemical testing was exclusively offered at our Edinburgh facility, primarily supporting our European client base.
01/30/2013
Selecting the appropriate animal model for your studies is critical to the success of your research. This is why, in 2011, our Model Evaluation Program was created to offer researchers a risk-free opportunity to evaluate the quality of our animal models prior to allocating valuable budget money or study resources.
01/22/2013
Cell lines requiring direct or indirect contact with feeder cells, conditioned medium or passage in animals can potentially get contaminated with heterologous cells from a different species. Cell lines can also get contaminated during routine culture. Check the identity of your cell lines with Cell Line Examination and Report (CLEAR) PCR Panel, which can detect interspecies contamination of less than 0.5% using TaqMan® PCR assays. Cells that can be differentiated include those originating from mouse, rat, Chinese hamster, Golden Syrian hamster, human and nonhuman primate (NHP) species.
01/15/2013
Charles River offers biomarker services ranging from assay development to GXP validation on multiple platforms on a variety of preclinical samples to support your drug discovery and development needs.
01/07/2013
Charles River offers an endothelial injury rat model of atherosclerosis. Additionally, we can carry out atherosclerosis studies to assess anti-atherosclerotic agents in ApoE-/- and LDLR-/- mice.
01/02/2013
Our recently validated rat and mouse models of rheumatoid arthritis, including collagen-induced arthritis (CIA) and collagen antibody-induced arthritis (CAIA), are the most requested assays in the RA field.
12/13/2012
Charles River Biopharmaceutical Services (BPS) is pleased to announce a new partnership with Batavia.
11/07/2012
The Charles River Endotoxin and Microbial Detection (EMD) division is pleased to introduce the first fully automated robotic system developed specifically for high-volume endotoxin testing in the central QC lab: the Endosafe® Nexus™.
11/02/2012
Our recently developed 128 SNP panel assays polymorphisms between B6 substrains including C57BL/6NCrl, C57BL/6NTac, C57BL/6NJ, C57BL/6J, and C57BL/6JOlaHsd.