Featured Stories

Two New Robust Models Available to Evaluate COPD or Asthma

05/14/2012

By combining long-standing expertise with new research solutions, Charles River facilitates drug development in these important disease areas. Our recently validated rodent models provide rapid, cost-effective methods for evaluating the potential efficacy of novel anti-inflammatory agents targeting COPD or asthma conditions.

New Endpoints Available for Assessment of Muscle and Peripheral Nerve Components of the Locomotor System

05/10/2012

In response to the growing interest in restoring or preserving not only bone quality but also muscle function in aging or debilitated people, Charles River is expanding our focus beyond the evaluation of bones to now also include other components of the locomotor system.  Our new offerings include various novel applications of imaging, biochemical and histomorphometric modalities, as well as electrophysiology measurements (nerve conduction and electromyography) to evaluate the locomotor unit. This expanded focus will allow us to characterize either pharmacologic or adverse effects of xenobiotics.

Ocular Coherence Tomography (OCT): New Insights in Ocular Research

05/04/2012

Charles River leverages ocular coherence tomography (OCT) technology to offer advanced in vivo microscopic evaluation. This technology helps identify drug toxicity and efficacy by capturing morphologic changes, resulting in a better understanding of a drug’s effect within the eye.

Charles River Now Offers MucilAir™ Human Airway Toxicity Test

04/24/2012

MucilAir (Epithelix) is an in vitro airway model with morphology and functions mirroring the tracheobronchial epithelium. It has potential applications in inhalation toxicity testing and pharmaceutical lead development, where it may be used to identify potential airway toxicants and facilitate in vivo dose range finding.

Charles River Partners with GENEWIZ

04/16/2012

GENEWIZ is a leading global contract research organization, offering DNA sequencing, gene synthesis, molecular biology, genomic, GLP regulatory and bioinformatics services. Their mission is to contribute to the advancement of life sciences and technologies by making research more productive and cost-efficient through their high-quality, scalable services. Clients will benefit from this partnership by receiving Charles River's expertise in cell and viral bank characterization with the added option of GENEWIZ's industry-leading Next Generation Sequencing (NGS) services.

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