When targeting genes, drug developers may opt for knockdown via CRISPR or silencing via RNAi. These weapons, however, may fit different battle plans.
Don’t fall into the cell line misidentification trap. Authenticate! What you don’t know–or what you refuse to acknowledge–will hurt you.
A string of acquisitions has revenue rolling at Charles River Laboratories, and the CRO has inked another M&A deal it hopes will pay off with a larger market share.
In this interview, James Foster, chairman and CEO at Charles River Laboratories spoke about the Company's Q3 earnings, the acquisition of ChanTest and why the work we do is so important.
Institutions that work with lab animals should establish a “culture of care” to make sure animals are treated with compassion. Animal welfare isn’t just good for the animal; it also affects the quality of science and the lives of the people and animals that stand to benefit from the research.
GEN recently interviewed seven experts to learn just what makes a good mouse model for biopharmaceutical research and to find out for which applications and diseases better models are most needed.
Joseph Cornicelli, a Scientific Advisor of Charles River Discovery Services in the areas of inflammation and metabolic and cardiovascular diseases, weighs in on recent data that appear to dampen the health risks of obesity.
Complex biology cannot be modeled with simple, stand-alone in vitro systems. More sophisticated, physiologically relevant systems are needed.
50 years ago this year, scientists first connected an ancient sea creature to testing for life-threatening bacteria.
Nearly 50 years ago, scientists discovered the horseshoe crab's clotting response to bacterial toxins. Now, its blood is harvested in huge quantities to be used in a test to ensure medical products are not contaminated.