Laboratory & Analytical Sciences: Pharmacokinetics

Our dedicated Pharmacokinetics group works closely with other operational departments to provide pharmacokinetic data for animal and human radiolabelled studies, human clinical trials, and veterinary clinical studies in a timely fashion. Utilizing industry-standard WinNonlin^® software, we can provide the following services:

• Input into study design, including preclinical-to-clinical considerations (allometric scaling) utilizing information from preclinical toxicokinetic studies
• Non-compartmental pharmacokinetics
• Compartmental pharmacokinetics / simulations
• Ascending dose (assessment of dose proportionality)
• Repeat dose (assessment of multiple dose linearity)
• Bioavailability and bioequivalence
• Drug interaction studies
• Special populations
• Pharmacodynamic and PK/PD modelling
• Deconvolution

Our pharmacokinetic consultancy service provides advice and support for all aspects of clinical pharmacokinetics and is offered as part of a complete development program, as a full-service single-study package, or as a stand-alone service. Upon request, pharmacokinetic parameter estimation output and reports may include a comprehensive text interpretation of the data.

See also our Toxicokinetics and Preclinical Pharmacokinetics capabilities.

What's New

Charles River Laboratories Clinical Services -- Northwest Kinetics Achieves Mortara Certified Partner Status

Charles River Acquires Northwest Kinetics

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