Bioenergetics and Brain Metabolism in Preclinical Models of Neurological Disease

Oct 29 2013

Bioenergetic deficiency plays a pivotal role in degenerative central nervous system diseases, and therapeutic interventions carry a promise for improvement. Assessing the brain for changes in energy state is challenging, but noninvasive imaging has a great promise to this end. Surrogate markers for brain are nevertheless needed for translational testing and assessing a muscle is a promising alternative.

In this webinar, Charles River Discovery Research Services outlines tools for bioenergetic readouts in CNS preclinical testing, with example data from in vivo MRI and MRS and PET imaging, as well as biochemical and systemic assays. The audience will learn about recent advances in rodent brain and muscle bioenergetic readouts and their applications to efficacy testing.

Presenter

• Dr. Antti Nurmi, Director of Science
  Charles River Laboratories, Kupio, Finland

For more information and to register, please click here.