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Guarding the Heart The best time to discover that a drug has cardiovascular liabilities is early in the drug research process. Assays that identify toxicities in preclinical phases can help. Drug Discovery & Development – June 1, 2009
The cardiovascular system is a vital part of the human body. It is responsible for important tasks such as supplying nutrients, removing waste, distributing hormones and regulatory substances, maintaining osmotic balance and homeostasis. It is also one of the more delicate systems in the human body and can be impacted by both cardiovascular and non-cardiovascular drugs. As a result, drug development programs are complex and often require multidisciplinary research when assessing potential cardiovascular toxicity...Read the full article.
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charles river preclinical services, cardiovascular, drug development, drug toxicity, cardiovascular medications, early discovery screening, in vitro imaging, in vivo imaging
Drug Discovery & Development: Guarding the Heart
The article, “Guarding the Heart” from the June issue of Drug Discovery & Development, discusses the complex nature of cardiovascular drug development and the multidisciplinary research approach to assessing potential cardiovascular toxicity.