Developmental and Reproductive Toxicology (DART) Capabilities Including Enhanced Pre- and Post-Natal Development
April 12, 2011 - Charles River Preclinical Services Nevada has over 20 years of experience conducting large animal reproductive toxicology studies using various routes of dose administration. These studies are performed using internationally recognized guidelines, including the International Conference of Harmonization (ICH). Our collective scientific knowledge can be utilized to create well-planned study designs that result in quality reports to support your biopharmaceutical research for international product registrations.
We offer a full-range of GLP study designs, including:
Our Preclinical Services team in Nevada is a world leader in the evolution of resource-saving, enhanced PPND studies. This design reduces use of animals by combining the EFD with the PPND study and has attained regulatory acceptance as an optimal design for biopharmaceuticals. Over the last three years, we have conducted ten of these specialized studies for sponsors, resulting in significant reductions in animal usage and costs.
For more information about our DART capabilities, click here. To request a proposal, email us at email@example.com.
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We offer a package of well-established, state of the art in vitro mode of action assays that are suitable for early phase biocomparability studies, lot release and stability. These tests can accelerate the time it takes to get a new product ready for market submission.
Charles River has developed and optimized the RT-PCR test for vertically-transmitted poultry pathogens for testing SPF flocks as defined by the PhEur 5.2.2.
May 20–May 22
Please visit Charles River tabletop #611 to discuss our full portfolio of products and services, including our Preclinical Services, as well as our Biopharmaceutical Services, which deliver client-focused solutions for the specific testing and manufacturing requirements of your biologic.
May 23–May 23
This full-day seminar encompasses selected topics from our Charles River Short Course on Laboratory Animal Science. We would like to acknowledge Michigan State University for hosting this event and extend our heartfelt thanks to guest speaker Dr. Danielle Ferguson.
This position is responsible for serving as a as a study director (SD), project scientist (PS) and/or principal investigator (PI) in the direction and execution of assigned studies in compliance with GLP regulations as they apply to the conduct of nonclinical research; coordinating all phases of the study planning process with appropriate departments; generating high-quality project plans, protocols, amendments and reports appropriate for assigned studies; reviewing, interpreting, integrating and presenting data on assigned studies; and functioning as contact for the planning and execution of sponsor interaction related to assigned studies, including proposal management and study scheduling, conduct and reporting.
This position is responsible for managing international aspects of US Federal income tax compliance; assisting with international tax planning, including identification of planning opportunities, designing and implementing plans, and transfer pricing process; overseeing quarterly ETR forecast process; and participating in the tax provision process, including assessment of tax risks, documentation of key positions, and review of non-US tax provision submissions.
Charles River Laboratories, Inc.