Developmental and Reproductive Toxicology (DART) Capabilities Including Enhanced Pre- and Post-Natal Development
April 12, 2011 - Charles River Preclinical Services Nevada has over 20 years of experience conducting large animal reproductive toxicology studies using various routes of dose administration. These studies are performed using internationally recognized guidelines, including the International Conference of Harmonization (ICH). Our collective scientific knowledge can be utilized to create well-planned study designs that result in quality reports to support your biopharmaceutical research for international product registrations.
We offer a full-range of GLP study designs, including:
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embryo-fetal development (EFD)
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pre- and post-natal development (PPND)
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male/female reproductive toxicology
Our Preclinical Services team in Nevada is a world leader in the evolution of resource-saving, enhanced PPND studies. This design reduces use of animals by combining the EFD with the PPND study and has attained regulatory acceptance as an optimal design for biopharmaceuticals. Over the last three years, we have conducted ten of these specialized studies for sponsors, resulting in significant reductions in animal usage and costs.
For more information about our DART capabilities, click here. To request a proposal, email us at askcharlesriver@crl.com.