Charles River Offers Cutting-Edge Mass Spectrometry Detector
August 6, 2009 – In keeping with the Charles River commitment to staying at the forefront of innovative bioanalytical services with state-of-the-art equipment and expertise, Charles River is pleased to announce the introduction of the AB SCIEX QTRAP™ 5500 LC-MS/MS system.
The QTRAP™ 5500 instrument is the latest generation technology from the Applied Biosystems/MDS Analytical Technologies joint venture. Capable of functioning as a standard triple-stage quadrupole mass spectrometry (MS) instrument, the QTRAP™ 5500 provides some of the most sensitive and robust assays in routine PK/TK testing. Additionally, the system offers the most sensitive linear ion trap, enabling MS3 quantitation for an additional level of selectivity, for example, when sample preparation fails to eliminate all interferents.
The high scan speeds and redesigned electronics make this an ideal MS detector for Ultra High Performance Liquid Chromatography (UPLC) without compromising data points across the chromatographic peak. As such, the two QTRAP™ 5500 systems implemented at Charles River have been coupled with Agilent Technologies 1200 Rapid Resolution Liquid Chromatography (RRLC) systems, thereby increasing the throughput capacity and further enhancing the available sensitivity.
The integrated trap functionality will also enable Charles River to expand on its already extensive biomarker analysis offerings and to further enhance the metabolite identification services, which enables identification of a greater number of metabolites in a shorter period of time.
The completely redesigned instrument, incorporating the curved LINAC™ collision cell, has reduced the footprint, allowing Charles River to accommodate a greater number of instruments in the same space. This improvement will in due course enable reductions in the infrastructure costs, with these savings ultimately being passed onto our customers without any compromise to scientific quality and excellence.