Charles River Unveils Endosafe®-PTS™ Glucan Assay

May 13, 2009 – We are proud to offer a new test to help ensure that your products are as free of contaminants as possible. Recent inspections have indicated a need to verify the absence of glucans. The Endosafe®-PTS™ glucan assay is a rapid test designed for investigational purposes to validate that your products are free of (1,3)-β-D glucans.

(1,3)-β-D glucan molecules can be found in the cell walls of most yeast and mold and can induce inflammatory responses. These glucans contaminate cell culture fluid, yeast protein production, air quality samples, and cellulose filter preparations. Glucans can cause false positive results in LAL assays triggering OOS investigations.

Our new PTS™ glucan assay allows you to quickly and easily quantify these glucans, leading to better process monitoring and faster OOS resolutions. Our glucan cartridges have a sensitivity range of 10-1,000 pg/ml, yield results in less than 30 minutes, and can be run on the same Charles River PTS™ reader that is used for endotoxin detection and Gram identification. 

This new product offering is in addition to the glucan-specific buffer that we already offer for those compounds that you know in advance have a strong possibility of being contaminated by glucans.

For more information about our new glucan assay or about our line of rapid endotoxin testing products, please call 1.877.CRIVER.1 (1.877.274.8371) or click here.