Edinburgh Facility Enhances Quantitative Whole-Body Autoradiography Capabilities

July 28, 2010 - Charles River Preclinical Services (PCS) Edinburgh has acquired new equipment to enhance its Quantitative Whole-Body Autoradiography (QWBA) program. The facility has obtained a Typhoon™ FLA 7000 scanner (GE Healthcare) and the CryoJane® Tape-Transfer System (Leica). These new additions will increase our capacity and capabilities for investigating tissue distribution and histology.

The Typhoon™ FLA 7000 scanner is a fast laser scanner optimized for quantitative phosphor imaging, ECL Plus Westerns, visible single fluorescence and gel documentation. It offers high speed (20 x 40 cm gel in 2.5 minutes) with high sensitivity (up to 25 μm resolution) for accurate quantification of closely spaced targets and full visible fluorescence with 473/532/635/650 nm excitation and up to 25 µm resolution for gel and blot imaging.

The CryoJane® Tape-Transfer System is an add-on for existing cryotomes and eliminates the problems normally encountered during cutting and staining frozen tissue sections by utilizing cold adhesive tapes and slides. This process produces a frozen section with minimal ice crystal artifact and the cellular structures preserved.

For more information about this new equipment or to learn more about the variety of other services PCS provides, please contact us at askcharlesriver@crl.com.