Photo Documentation of Hair Loss Pattern in the SHO® Mouse
April 4, 2011 - In 2007, Charles River’s Research Model group intercrossed the Crl: HA-Prkdcscid and the Crl: SKH1-Hrhr stocks to create a hairless and immunodeficient strain called the SCID Hairless Outbred (SHO®) mouse*. In 2010, we launched a study designed to provide photographic documentation of the hair loss pattern observed in these mice.
In this 28-day observational study, two litters of SHO® pups were observed from birth. Litter A contained 13 newborn pups and Litter B contained 9. Pups were randomly selected from Litter A and B and photographs were taken of each pup on day 1 (birth) and finished on day 24. Along with photographic documentation, all pups were screened for health and physical abnormalities.
To view the data from this study, click here.
*Charles River patent pending
SHO Mouse: A Double-Homozygous SCID Hairless Outbred Model
Characterization of a New Hairless SCID Mouse
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Clinical pathology data can assist you in selecting the most appropriate model for your study and can provide important information on the physiology and health of your research animals.
We are now the exclusive distributor of the TARGATT™ mouse. The TARGATT mouse is a transgenic mouse designed to produce animal models with investigator designed exogenous DNA sequences knocked-in to a specific site.
Jun 10–Jun 13
Visit us in booth #091 to learn more about our recent innovations including expanded diagnostic capabilities, a new online portal connecting clients with their colonies and a deep-rooted commitment to humane care.
May 28–Jun 01
The International Bone and Mineral Society (IBMS) and the Japanese Society for Bone and Mineral Research (JSBMR) are excited to sponsor the second joint scientific meeting by the two organizations.
May 23–May 23
This full-day seminar encompasses selected topics from our Charles River Short Course on Laboratory Animal Science. We would like to acknowledge Michigan State University for hosting this event and extend our heartfelt thanks to guest speaker Dr. Danielle Ferguson.
This position is responsible for serving as a as a study director (SD), project scientist (PS) and/or principal investigator (PI) in the direction and execution of assigned studies in compliance with GLP regulations as they apply to the conduct of nonclinical research; coordinating all phases of the study planning process with appropriate departments; generating high-quality project plans, protocols, amendments and reports appropriate for assigned studies; reviewing, interpreting, integrating and presenting data on assigned studies; and functioning as contact for the planning and execution of sponsor interaction related to assigned studies, including proposal management and study scheduling, conduct and reporting.
This position is responsible for managing international aspects of US Federal income tax compliance; assisting with international tax planning, including identification of planning opportunities, designing and implementing plans, and transfer pricing process; overseeing quarterly ETR forecast process; and participating in the tax provision process, including assessment of tax risks, documentation of key positions, and review of non-US tax provision submissions.
Charles River Laboratories, Inc.