Respiratory Models and Respiratory Drug Research | Charles River

respiratory disease 

Millions of individuals globally are affected by chronic respiratory diseases such as asthma and COPD. The number of individuals suffering from allergies involving the respiratory tract is also rising at an alarming rate. 

Charles River has a wide range of capabilities to support your respiratory research.

Global Facilities, Expert Staff

With more than 40 inhalation toxicology dosing suites globally, we offer the full range of preclinical study designs:

  • acute to carcinogenicity
  • pharmacology
  • reproductive
  • neonatal and juvenile 


MucilAir
Human Airway Toxicity Test

MucilAir™ (Epithelix) is an in vitro airway respiratory model with morphology and functions mirroring the tracheobronchial epithelium. It has potential applications in inhalation toxicity testing and pharmaceutical lead development, where it may be used to identify potential airway toxicants and facilitate in vivo dose range finding. Learn more.

Two New Robust Respiratory Models Available to Evaluate COPD or Asthma

Charles River has a number of respiratory system models, including the recently validated rodent models for evaluating the potential efficacy of novel anti-inflammatory agents targeting COPD or asthma conditions. Learn more.

Additional respiratory model:


Contact Information

To inquire about our integrated respiratory research services, please contact us at 1.877.CRIVER.1 or askcharlesriver@crl.com.

Related Information

To access exclusive respiratory-related content, including the items listed below, log in to The Source℠. If you are not a member of The Source, click here to register.

  • Webinar - Preclinical Pulmonary Inflammation Models (October 2010)
  • Webinar – Neonatal and Juvenile Inhalation Toxicology Studies (March 2011)
  • Researcher 202: Inhaled Powder Delivery for Preclinical Toxicity Testing (April 2012)
  • Researcher 187: Experience and Expertise in Juvenile Toxicology Studies (March 2011)
  • Poster: MucilAir™, an In Vitro Model for Assessment of Human Airway Toxicity, Evaluated Using Model Irritant Sodium Dodecyl Sulfate (SDS)
  • Podcast: Evaluation of MucilAir™ as an In Vitro Model of Human Airway Epithelium
Discover the full range of Charles River Products and Services
The Source

For more information, contact us at:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

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