Central Nervous System (CNS) Mouse and Rat | Charles River Discovery Services

Spinal Cord Injury Models 

Charles River Discovery Services' spinal cord injury (SCI) models apply NYU impactor or hemisection in order to induce functionally and histologically relevant injury. The ability to look at short-term histological changes as well as long-term and more comprehensive outcomes within an extensive functional battery offers powerful tools to evaluate elements of neuroprotection and neuroregeneration. All studies can be customized and adjusted as per client needs.

Models for Spinal Cord Injury

  • Mild/Moderate T10 Contusion injury
  • Severe T10 Contusion injury
  • Hemisection model (unilateral injury)


Example Study Paradigm of Spinal Cord Injury Model

Diagram outlining an example study paradigm using our Spinal Cord Injury model

 

Click here to see a diagram outlining an example study paradigm using our Spinal Cord Injury model.

 

 

Data

BBB Score in a Spinal Cord Injury Model

 

BBB Score

 

 

Total Injury Volume of Spinal Cord Sections

 

 

Total Injury Volume of Spinal Cord Sections

 

 

 

For more information about our models used to research spinal cord injuries, please contact us at 1.877.CRIVER.1 or askcharlesriver@crl.com.

Discover the full range of Charles River Products and Services
The Source

For more information, contact us at:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

view all

News & Events

view all
Jun 13 - Neurological Biomarkers in Efficac...
Jun 06 - GLP-Compliant ELISpot and FluoroSp...
Jun 24-Jun 26 - London, UK - Skin Forum 2013
Jun 21-Jun 25 - Chicago, IL - American Diabetes Association’s 73rd Scientific Sessions
Sep 09-Sep 11 - Carlsbad, CA - 19th Annual Biotechnology-Derived Therapeutics Perspecti...
Jun 28-Jun 28 - Frankfurt, Germany - Seminar: Health Monitoring of Laboratory Animals

Charles River Laboratories, Inc.