Mouse & Rat Breeding & Aging Services | Charles River
 

speed congenics


 
 

SNP panels are one method of speed congenicsBackcrossing your animal model reduces genetic variability and is often an essential step in the research process. At Charles River, we offer a speed congenics service, MAX-BAX®, that can dramatically reduce the time required (by up to 18 months) to fully backcross a line. This reduction is acheived by selecting animals with preferred genetic background as breeders for the next generation, resulting in a fully backcrossed animal in only five generations instead of ten.

 

Backcrossing Generations Recipient Genome % Comparison

Generation Traditional Backcross Speed Backcross
F1 50% 50%
N2 75% 81%
N3 87.5% 94%
N4 93.75% 99%
N5 96.88% 99.9%
N6 98.44%
N7 99.22%
N8 98.61%
N9 99.81%
N10 99.9%
 

Our MAX-BAX® program can be performed via custom-designed, highly polymorphic Single Nucleotide Polymorphism (SNP) or Microsatellite panels, giving you the flexibility to select a technique that best fits your needs. By choosing Charles River for your speed congenics needs, you gain access to our highly-skilled project management team that will help you backcross your line quickly and affordably so you can focus on your research.

 
 
 
 
 
 
 
 

 

   
 
   
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For more information, contact us at:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

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Want to find out how much your project will cost? Fill out a quote request form and one of our project specialists will be in touch with you shortly.
Detailed information about how our speed congenics program works.
When you're ready to start a project, complete this form and our project management staff will take care of the rest.

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