Backcrossing your animal model reduces genetic variability and is often an essential step in the research process. At Charles River, we offer a speed congenics service, MAX-BAX®, that can dramatically reduce the time required (by up to 18 months) to fully backcross a line. This reduction is acheived by selecting animals with preferred genetic background as breeders for the next generation, resulting in a fully backcrossed animal in only five generations instead of ten.
Backcrossing Generations Recipient Genome % Comparison
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Our MAX-BAX® program can be performed via custom-designed, highly polymorphic Single Nucleotide Polymorphism (SNP) or Microsatellite panels, giving you the flexibility to select a technique that best fits your needs. By choosing Charles River for your speed congenics needs, you gain access to our highly-skilled project management team that will help you backcross your line quickly and affordably so you can focus on your research.