We know that reproductive performance of genetically engineered rodents can often be unpredictable. This unpredictability can suddenly leave you with animals that are no longer able to reproduce naturally. At Charles River, we offer a comprehensive rescue program specifically designed to overcome both male and female fertility challenges. By employing the latest technology, you can have confidence that we will successfully rescue your valuable strain.
The first step to overcoming fertility issues is to diagnose the cause. Our male and female fertility assessment can help you do exactly that. Components of this program can include sperm analysis, observational mating, and breeding record evaluation. Once the cause of the reproductive deficiency is identified, rescue options, including ovarian transplantation, in vitro fertilization (IVF) (both natural and laser-assisted), and intracytoplasmic sperm injection (ICSI) can be explored. We will keep you informed through every step of the process and, in most cases, return viable breeders to you in approximately 15 weeks to effectively restore your colony.