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Charles River combines experienced pathologists with a highly trained technical staff and well-designed laboratories to offer pathology services in the specialized area of neuropathology. We provide assistance in study design, development strategies, and regulatory submissions for a wide variety of compounds affecting the nervous system. Each year, our scientists conduct over 30 GLP-compliant neuropathology studies in support of FDA and EPA regulatory submissions. We have developed several unique capabilities that allow us to provide exceptional support to companies developing compounds with neurological implications.
Services
- Whole body perfusion
- Specialized nerve tissue embedding
- Specialized staining capabilities
- Electron microscopy (transmission electron microscopy and scanning electron microscopy)
- Morphometric analysis
- Immunohistochemistry
Additional information about our Neuropathology capabilities is available in The SourceSM, our new online scientific and educational information center. To register for The SourceSM, please click here. If you are already a member, click here to login.
If you have any questions, please contact us at 1.877.CRIVER.1 or askcharlesriver@crl.com.
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Neuropathology, neuropathology studies, neuropathological assessments, GLP-compliant, Whole-body perfusion, Brain sectioning, nerve tissue embedding , Ultrastructural analysis, Morphometric analysis, immunohistochemistry, neural perfusion, Fluoro-Jade B, Fluoro-Jade C, glial fibrillary acidic protein, microtubule-associated protein 2, neurodegeneration, H&E stains, Bielschowsky blue, Luxol fast blue, cresyl violet, X-gal, Y chromosome in situ hybridization, morphometric analysis, Morphometry, neuroscience
GLP-Compliant Neuropathology Studies | Charles River Pathology Associates
Each year, our scientists conduct over 30 GLP-compliant neuropathology studies in support of FDA and EPA regulatory submissions. We have developed several unique capabilities to assist companies developing compounds with neurological implications.