Preclinical Toxicology Studies | Charles River

dermal services 

With global capability and extensive experience, Charles River offers a range of services to support the development of your dermal product.  Our portfolio of services range from in vitro screening to in vivo toxicology and metabolism in support of product development in the pharmaceutical, chemical, agrochemical, consumer product and animal health sectors. We continually work to develop and apply new testing models, especially in the field of replacement technologies.

Our services include, but are not limited to:

  • In vivo and in vitro test systems
    • Human and animal skin
    • Skin constructs
    • Mice, rats, guinea pigs and pigs
    • Swiss nude mice, hairless guinea pigs, rats and mice
  • In vitro models
    • Percutaneous absorption and distribution
    • Metabolism
    • Formulation screening
    • Irritation & corrosivity
  • In vivo models
    • Radiolabeled studies, QWBA
    • ADME in rodents & non-rodents
    • Metabolite profiling & ID
  • General Toxicology
    • Irritation with multiple test systems
    • Sensitization
    • Acute to carcinogenicity
    • Open, semi-occluded and occluded administrations
  • Photoxicology
  • Study Support Services
  • Formulation experience
    • Solids, liquids, gels, solvents, paints, hair dyes, creams, ointment
    • Transdermal delivery systems

 

If you have any questions, please contact us at 1.877.CRIVER.1 or askcharlesriver@crl.com.

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For more information, contact us at:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

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News & Events

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May 08 - Comparability Studies for Monoclon...
May 02 - Real Time Polymerase Chain Reactio...
May 20-May 22 - San Diego, CA - 2013 American Association of Pharmaceutical Scientists ...
May 23-May 23 - East Lansing, Michigan, USA - The Ins and Outs of Transgenic Colongy Ma...

Charles River Laboratories, Inc.