Preclinical Toxicology Studies | Charles River

inhalation toxicology 

If you are looking to contract your inhalation toxicology study, Charles River can manage your entire inhalation testing program, as well as: 

  • Support the selection of drug formulation and delivery systems
  • Assist in dosage estimation for animal studies
  • Conduct special studies to demonstrate efficacy or pharmacotoxicity

Preclinical Inhalation Toxicology Study Types Offered

Since 1968, we have successfully conducted thousands of inhalation toxicology studies and offer the following study designs:

Inhalation Toxicology Study Types Offered

Nose-only, oronasal and head-only

Intranasal

Acute to chronic toxicity, plus carcinogenicity

Immunologic sensitization via inhalation

Neonatal inhalation

Reproductive inhalation

Anti-asthmatic efficacy

Radiolabelled aerosol studies

Intratracheal

 


Ranging from acute to carcinogenicity, these inhalation toxicity study types utilize:  

  • All laboratory species
  • Powder, liquid, metered dose inhaler or vapor formulations

 

Global Facilities

Charles River has the largest inhalation toxicology facilities in the world. Our inhalation testing facilities are equipped with:  

  • Rodent inhalation dosing rooms, with adjacent husbandry space
  • Dedicated sections for nonrodent studies
  • Dosing suites with customized generation and exposure systems for delivery of test atmospheres

 

Expert Staff

Our scientific professionals have a deep understanding of inhalation toxicity testing program design and are led by a management team with an established reputation.

  • Formulation Scientists – support all of our studies and have experience in micronizing and blending powder formulations
  • Analytical Scientists – characterize inhaled compounds, including liquids, powders, vapors and gases
  • In-House Experts – assist with customized generation and exposure systems

 

Contact Information

To inquire about contracting an inhalation toxicology study with us, please contact us at 1.877.CRIVER.1 or askcharlesriver@crl.com


Related Inhalation Toxicology Information

  • Webinar Replay - Preclinical Pulmonary Inflammation Models  

    (Available only in the SourceClick here to log in or click here to register.)

  • Webinar Replay - Neonatal and Juvenile Inhalation Toxicology Studies  

    (Available only in the SourceClick here to log in or click here to register.)

Source logoAdditional information about our Inhalation Toxicology capabilities is available in the Source, our new online scientific and educational information center. To register for the Sourceclick here. If you are already a member, click here to login.

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The Source

For more information, contact us at:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

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Charles River Laboratories, Inc.