Adult and developmental neurotoxicology testing at Charles River encompasses a broad range of products, including pharmaceuticals, biologics, biomaterials, chemicals, and agrochemicals. Routine screening evaluations are conducted as stand-alone studies or as components of regular subchronic and chronic safety studies. Backed by the largest historical control database for tests in developmental neurotoxicity studies, Charles River's offerings in the area of functional teratology, pediatric evaluations, and adult screening are unmatched in the industry.
In addition to standard dose routes, specialized treatment routes such as epidural, intrathecal, intracerebral, and continuous intravenous infusion, as well as inhalation and dermal exposure, can be used in rodent and nonrodent species to mimic the clinical route.
- Functional Observational Battery (FOB)
- Clinical observations
- Motor activity
- Learning and memory
- Sensory evaluation
- Motor coordination
- Paraffin and plastic-embedded
- Brain morphometry
- Cytochemical markers
- Electron microscopy
- Image analysis
Additional information about our Neurotoxicology capabilities is available in The SourceSM, our new online scientific and educational information center. To register for The SourceSM, please click here. If you are already a member, click here to log in.
If you have any questions, please contact us at 1.877.CRIVER.1 or firstname.lastname@example.org.