SCID Hairless Outbred (SHO®) and SCID
Hairless Congenic (SHC™) mice preserve the immunodeficient status of a SCID (e.g., B- and
T-cell deficient) but exhibit a hairless phenotype.
Why are these models valuable?
Engraftment efficiency of human tumors is higher in SCID mice than in more commonly used nude mice due to the deficiency of not only T cells, but also B cells. However, the use of SCID mice in oncology research is hindered by their hair coat, which makes tumor measurement and in vivo imaging difficult. The SHO® and SHC™ models provide unimpeded access to the skin of the animals, thus enabling more accurate tumor measurement and efficient in vivo imaging. For more information on our full range of immunodeficient models, click here.
If you would like to determine if our hairless SCID mice are right for your research, contact us at email@example.com and ask about our evaluation program.