ORIGIN The hairless SCID mouse was produced by Charles River Research Models in 2007 by inter-crossing the Crl:HA-Prkdcscid and Crl:SKH1-Hrhr stocks. The resulting animals are homozyogous for the Prkdcscid and the Hrhr mutations and thus exhibit the severe combined immunodeficiency phenotype characteristic of SCID mice and are also hairless.
STRAIN CODE 474
COAT COLOR Hairless, albino background
RESEARCH APPLICATIONtumor biology and xenograft research
BREEDING LOCATIONUS, Germany
ORDERING INFORMATIONPlease call 1.800.LAB.RATS if you would like to place an order.
For additional information about SCID Hairless Outbred (SHO™) mice, please contact Technical Services at 1.800.338.9680 or firstname.lastname@example.org.
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Our study, presented at the 2013 Experimental Biology Conference, focuses on the phenotype and genotype comparison for C57BL/6N substrains contributing to the International Mouse Phenotyping Consortium (IMPC).
Clinical pathology data can assist you in selecting the most appropriate model for your study and can provide important information on the physiology and health of your research animals.
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This position is responsible for serving as a as a study director (SD), project scientist (PS) and/or principal investigator (PI) in the direction and execution of assigned studies in compliance with GLP regulations as they apply to the conduct of nonclinical research; coordinating all phases of the study planning process with appropriate departments; generating high-quality project plans, protocols, amendments and reports appropriate for assigned studies; reviewing, interpreting, integrating and presenting data on assigned studies; and functioning as contact for the planning and execution of sponsor interaction related to assigned studies, including proposal management and study scheduling, conduct and reporting.
This position is responsible for managing international aspects of US Federal income tax compliance; assisting with international tax planning, including identification of planning opportunities, designing and implementing plans, and transfer pricing process; overseeing quarterly ETR forecast process; and participating in the tax provision process, including assessment of tax risks, documentation of key positions, and review of non-US tax provision submissions.
Charles River Laboratories, Inc.