
SCID Hairless Congenic (SHC™) Mouse
CB17.Cg-PrkdcscidHrhr/IcrCrl
ORIGIN
The hairless SCID congenic was created in 2009 by Charles River Research Models by using marker-assisted accelerated backcrossing to place the hairless gene (Hrhr) present in the Crl:SKH1-Hrhr stock onto a CB17/Icr-Prkdcscid/IcrIcoCr genetic background. These mice are homozygous for both Hrhr and Prkdcscid mutations, so exhibit the severe combined immunodeficiency phenotype characteristic of SCID mice and are also hairless.
COAT COLOR Hairless, albino background
RESEARCH APPLICATION
tumor biology and xenograft research
MHC HAPLOTYPE H2d
BREEDING LOCATION
US
ORDERING INFORMATION
Please call 1.800.LAB.RATS if you would like to place an order.
For additional information about SCID Hairless Congenic (SHC™) mice, please contact us at askcharlesriver@crl.com.