The FDA-licensed cartridges are pre-loaded with all of the reagents required to perform an LAL test on the Endosafe®-PTS™ portable spectrophotometer. This integrated testing system eliminates preparation of multiple reagents and reduces the opportunity for technician error.
The disposable cartridge contains four channels - two channels with CSE and LAL, which serve as the positive control channels, and two channels with LAL for testing of samples.
Click here to view a diagram of the PTS™ cartridge.
To perform the test, add 25µL of sample into all four sample reservoirs. The reader's internal pump moves the samples to the first reagent station for mixing. The pump then moves the samples to station 2 for mixing and then into the optical cells of the cartridge to be read kinetically.
Since there is no need to create a standard curve, create a positive product control, and reconstitute LAL, there is no need for a negative control by the user. However, it is recommended that when performing sample dilutions the diluent be tested for endotoxin prior to use.
PTS™ cartridges are available in four sensitivities:
- .005 EU/mL
- .01 EU/mL
- .05 EU/mL
- .1 EU/mL