Embryology | Genetically Engineered Models & Services | Charles River

rederivation 

Embryo Selection - Only the highest quality two-cell embryos are used for rederivation  

At Charles River, we know that healthy, pathogen-free animals are key to producing reliable, repeatable research results. Our rederivation service removes adventitious organisms such as viruses, bacteria, and parasites in your mice and rats. All rederived animals from Charles River meet our VAF/EliteTM health status and are maintained in the biosecurity of an isolator environment to protect the health of the colony. 

Our service options include:

Embryo Rederivation Services

Best used for homozygous lines, lines with multiple genetic mutations, or rat rederivation. Non-rederived live colony is maintained until the deliverables are met.
Service Deliverables
Mouse
Rederivation I
At least 2 visibly pregnant, embryo recipient females.
Mouse
Rederivation II
At least 10 rederived animals with a complete health report.
Mouse
Rederivation III
At least 10 rederived animals with a complete health report. Expansion of a homozygous colony prior to rederivation is included.
Rat Rederivation I At least 10 rederived animals with a complete health report.
Rat Rederivation II At least 10 rederived animals with a complete health report. Expansion of a homozygous colony prior to rederivation is included.
Sperm Rederivation Services
Best used for non-homozygous, single mutation mouse lines.
Service Deliverables
Mouse Sperm Rederivation I At least 2 visibly pregnant, embryo recipient females and cryopreserved sperm.
Mouse Sperm Rederivation II At least 10 rederived animals with a complete health report and cryopreserved sperm.

In addition to our standard mouse rederivation options, we also offer IVF-based rapid colony expansion to deliver larger colonies on demand.

With over twenty years of experience rederiving mice and rats, our staff of scientists and project managers is ready to help you get the animals you need, with the health status your facility requires, in a timely and cost effective manner.

Discover the full range of Charles River Products and Services
The Source

For more information, contact us at:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

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Detailed information about our rederivation services and procedures.
Details specific to eliminating unwanted pathogens such as RRV from your rat colonies.
When you're ready to start a project, complete this form and our project management staff will take care of the rest.

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RMS Specialist Montreal, Canada

Charles River Laboratories, Inc.