ORIGIN
Inbred from a congenic control group of Dahl/SS rats (SS/JrHsd) obtained from Dr. Theodore Kurtz (UCSF, CA) which were originally derived from the Harlan SS/Jr colony. Maintained at the Medical College of Wisconsin since 1991, this strain has undergone considerable marker-selected breeding to eliminate residual heterozygosity and genetic contamination. To confirm homozygosity, the strain was tested with 200 microsatellite markers (genome-wide scan at 20cM) all of which were homozygous for all regions tested. (Cowley et al. 2000, Physiol. Genomics 2:107-115). To Charles River in 2001.
STRAIN CODE 320
COAT COLOR White (albino)
RESEARCH APPLICATION
hypertension, diastolic heart failure, nephropathy
CONTROL The SS-13BN is the normotensive control for the Dahl/SS rat.
Note: Dahl/SS stock animals are fed AIN-76a .3% sodium diet from weaning (~3 weeks of age) until they are shipped. If you do not want them fed this diet, please let us know at least one week prior to weaning.
BREEDING LOCATION
US
ORDERING INFORMATION
Please call 1.800.LAB.RATS if you would like to place an order.
For additional information about Dahl/Salt Sensitive (Dahl/SS) rats, please contact Technical Services at 1.800.338.9680 or comments@crl.com.