Research Animal Models | Charles River

CORE 


The CORE (Collection of Oncology Research Experiments) is an online library of peer-reviewed publications designed to help you find the most appropriate research model for your oncology cell lines. Search through the publications by first selecting your tissue type below. Simply select the cell line you want to reference and the publications will be listed by animal model. The publications were collected from various online resources and are non-curated.

Once you have identified the appropriate model for your research, take advantage of our Animal Model Evaluation Program to assess that model on your study at no cost and no commitment.

Bladder| Brain | Breast | Colon | Fibrosarcoma | Gastric | Head and Neck | Hepacellular | Leukemia/Lymphoma | Liver | Lung | Melanoma | Multiple Myeloma | Osteosarcoma | Ovarian | Pancreas | Prostate | Renal | Thyroid | Vulvar Epidermoid Carcinoma

fibrosarcoma

Cell Line: HT-1080

Athymic Nude Mouse

  • Role of Phosphoinositide 3-Kinase in the Aggressive Tumor Growth of HT1080 Human Fibrosarcoma Cells
    • Loss of Transgelin in Breast and Colon Tumors and in RIE-1 Cells by Ras Deregulation of Gene Expression through Raf-independent Pathways*

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        NU/NU Nude Mouse

      • Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells
      • The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
      • Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteins
      • Potent Oncolytic Activity of Raccoonpox Virus in the Absence of Natural Pathogenicity
      • Specific binding of TES-23 antibody to tumour vascular endothelium in mice, rats and human cancer tissue: a novel drug carrier for cancer targeting therapy

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        Fox Chase SCID Mouse (C.B.17 SCID)

      • Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

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          Fox Chase SCID Beige Mouse

        • Effect of the Multitargeted Receptor Tyrosine Kinase Inhibitor, ABT-869 [N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N-(2-fluoro-5- methylphenyl)urea], on Blood Pressure in Conscious Rats and Mice: Reversal with Antihypertensive Agents and Effect on Tumor Growth Inhibition
        • X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists

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            CD-1 Nude Mouse

          • Potent Oncolytic Activity of Raccoonpox Virus in the Absence of Natural Pathogenicity
          • Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice
          • Antiangiogenic Tumor Treatment: Early Noninvasive Monitoring with USPIO-enhanced MR Imaging in Mice

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            BALB/c Nude Mouse

          • Potent Oncolytic Activity of Raccoonpox Virus in the Absence of Natural Pathogenicity
          • Inhibition of Tumor Growth and Metastasis by an Immunoneutralizing Monoclonal Antibody to Human Vascular Endothelial Growth Factor/Vascular Permeability Factor

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              NOD SCID Mouse

            • Drug-Tolerant Cancer Cells Show Reduced Tumor-Initiating Capacity: Depletion of CD44+ Cells and Evidence for Epigenetic Mechanisms
            • Zebrafish as a Model for Cancer Self-Renewal
            • Myeloid-derived suppressor cells are implicated in regulating permissiveness for tumor metastasis during mouse gestation
            • A Model for Antimicrobial Gene Therapy: Demonstration of Human β-Defensin 2 Antimicrobial Activities In Vivo

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