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disease models by indication
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Animal Models of Disease
| Indication |
Relevant Models |
| Cardiovascular Disease |
SHHF |
| Fasting Hyperglycemia |
GK, Obese Prone Rat (OP-CD), Obese Resistant Rat (OR-CD), THE POUND MOUSE™, ZDF, ZSF1 |
| Hypercholesterolemia |
Dahl/SS, SHHF, SHR, SHROB, Stroke Prone SHR, THE POUND MOUSE™, ZDF, ZSF1, Zucker |
| Hyperinsulinemia |
Dahl/SS, GK, Obese Prone Rat (OP-CD), Obese Resistant Rat (OR-CD), SHHF, SHR, SHROB, Stroke Prone SHR, THE POUND MOUSE™, ZDF, ZSF1, Zucker |
| Hypertension |
Dahl/SS, FHH, Obese Prone Rat (OP-CD), Obese Resistant Rat (OR-CD), SHR, SHHF, SHROB, Stroke Prone SHR, ZSF1 |
| Hypertriglyceridemia |
Dahl/SS, SHHF, Obese Prone Rat (OP-CD), Obese Resistant Rat (OR-CD), SHR, SHROB, Stroke Prone SHR, ZDF, ZSF1, Zucker |
| Insulin Resistance |
Dahl/SS, GK, Obese Prone Rat (OP-CD), Obese Resistant Rat (OR-CD), SHHF, SHR, SHROB, Stroke Prone SHR, THE POUND MOUSE™, ZDF, ZSF1, Zucker |
| Nephropathy |
Dahl/SS, GK, SHHF, SHROB, Stroke Prone SHR, ZDF, ZSF1, Zucker |
| Non-Insulin Dependent Diabetes Mellitus (NIDDM) |
GK, SHHF, ZDF, ZSF1 |
| Obesity |
Obese Prone Rat (OP-CD), SHHF, SHROB, THE POUND MOUSE™, ZDF, ZSF1, Zucker |
| Polycystic Kidney Disease |
PCK |
In certain cases, the phenotype is expressed or enhanced when the animal is fed a specific diet. With our preconditioning services, you can purchase your animals ready to use and save valuable laboratory space for your actual study. During the preconditioning period, various phenotypic parameters can be measured and recorded on an “as needed” basis. In addition, surgical manipulations can be performed on the animals as part of the preconditioning process.
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Animal models of disease, disease models, research animal models, disease indications
Animal Models of Disease By Indication | Charles River
Charles River provides animal models of common human diseases for use in basic research and nonclinical drug discovery and development. This page sorts our disease models by indication of interest.
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For more information, contact us at: 1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com
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