Genetic Testing Services for Laboratory Animals | Charles River

strain specific genetic verification 

 

Non-Obese Diabetes

            • Non-obese diabetes (NOD) is a polygenic disorder with several loci contributing to this phenotype. Utilizing microsatellite analysis, we can verify the presence of markers linked to the loci associated with the disease state.

  

Research Models for Diabetic Research

  • Severe Combined Immunodeficiency (SCID) - SCID is the result of a spontaneous autosomal recessive mutation. Using PCR and restriction enzyme analysis, our assays can confirm the presence or absence of this point mutation.

 

  • Zucker Fatty Gene Verification (ZF and ZDF Rats) - With our PCR digest assay, we are able to distinguish between wild type, heterozygous, and homozygous animals before the fatty phenotype is displayed at six weeks. Learn more about the Zucker and ZDF Rat.
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For more information, contact us at:

1.877.CRIVER.1 (1.877.274.8371)
askcharlesriver@crl.com

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Charles River Laboratories, Inc.