compliance statements and certifications 

National Good Laboratory Practice (GLP) compliance monitoring authorities document the compliance status of nonclinical laboratories in different ways. The United States Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) document the compliance status of laboratories through inspection reports and post-inspectional correspondence. These documents are available from the respective agencies under the Freedom of Information Act. The FDA also maintains a historical list of nonclinical laboratory inspections that provides the agency’s classification of each inspection.

Many monitoring authorities outside the United States document the compliance of laboratories by the issuance of Statements of Compliance. These Statements of Compliance indicate that the laboratory has been inspected and found to be in compliance with GLPs. Charles River facilities located in Canada, Ireland, and the United Kingdom are subject to GLP monitoring by the European Agency for the Evaluation of Medicinal Products (EMEA), the Irish National Accreditation Board (INAB), and the Medicines and Healthcare products Regulatory Agency (MHRA), respectively. These GLP monitoring authorities issue Statements of Compliance. The following Statements of Compliance reflect the current status of the Charles River facilities operating in those countries mentioned above.

• Statement of GLP Compliance - Canada
• Statement of GLP Compliance - Edinburgh
• Statement of GLP Compliance - Ireland
• Certificate of GMP Compliance - Human Medicinal Products - Ireland
• Certificate of GMP Compliance - Veterinary Medicinal Products - Ireland
• Certificate of GMP Compliance - Human Investigational Medicinal Products - UK
• Certificate of GMP Compliance - Human Medicinal Products - US
• Animal Welfare Certification (April 2008) for Charles River Laboratories Preclinical Services Ireland, Ltd.