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Minimizing Cardiovascular Liabilities Throughout Drug Development
Drug Delivery Technology – October 2009
The various effects of pharmaceuticals on the cardiovascular system are currently a major topic of interest throughout the drug development industry. This cardiovascular focus is primarily due to the fact that drugs even those not specifically designed to directly affect cardiovascular function-can easily alter this fragile but vital organ system. As a result, specialized precautions must be taken throughout a drug discovery and development program. These precautions require the conduct of specific studies that can increase the overall complexity and require additional risk/benefit assessments. Potential cardiovascular toxicities can become more evident as a lead candidate enters the later stages of drug development...Read the full article.
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cardiovascular therapeutics, drug discovery and development, lead candidate selection, safety pharmacology, clinical assessment
Minimizing Cardiovascular Liabilities Throughout Drug Development
When considering the effects of pharmaceuticals on the cardiovascular system, specialized precautions must be taken, which require the conduct of specific studies that can increase the overall complexity and require additional risk/benefit assessments.