Charles River develops and produces antigens as well as polyclonal and monoclonal antibodies. Customers have the choice between cost-efficient complete packages or individual development and antibody production modules that are optimized for their specific application. Additionally, we offer antibody purification and labeling for small-scale through bulk production. Our experts will assist you throughout the entire antibody production process, as well as during additional antibody characterization. If you require a special service such as antibody fragmentation or gold coupling, we will be happy to discuss how we can meet your individual antibody production needs.
Success in the field of antibody production depends not only on the immunogenic potential of the antigen, but also factors like the housing and handling of the animals. Since animal stress can adversely impact antibody production, Charles River works hand-in-hand with the scientific community to optimize living conditions and handling procedures to reach the highest possible standards for minimizing the stress factor. Charles River uses animals from its specific-pathogen-free (SPF) breeding facilities for immunization, resulting in a minimized background signal of the serum and an identical genetic background. Furthermore, all procedures performed during immunization are described in our Standard Operation Procedures (SOPs) to ensure a high-quality product.
All antibody development projects are treated with strict confidentiality. Used animals, developed antigens, and monoclonal hybridoma cell lines remain the exclusive property of the customer.
For technical support or to place an order for antibody production services, please email antibody@crl.com.