Charles River Biopharmaceutical Service (BPS) recognizes the role modern biotechnology plays in the development of medicines and offers services to assist clients making these advances. BPS has over 15 years experience working with various recombinant proteins, including monoclonal antibodies and biosimilars, as well as vaccines, neurotoxins, hormones and anti-venoms. Areas of expertise include:
Cell Therapy
- Raw material testing
- Manufacture of cell banks and cell batches
- Full characterization and biosafety testing of cell banks and release testing of cell batches
Gene Therapy
- Cell bank manufacturing
- Cell line characterization and biosafety testing
- Cell storage services
- Virus seed manufacturing
- Virus product manufacturing
- Virus characterization and biosafety testing
- Virust storage services
- Release testing
Monoclonal Antibodies and Recombinant Proteins
- Raw material testing
- Cell banking manufacturing
- Cell line characterization and biosafety testing
- Cell storage services
- Bulk harvest testing
- Lot and final drug product release testing
- Process validation/viral clearance studies
- Protein characterization
- Stability testing
Human- and Animal-Derived Products/Materials
- Drug product release testing
- Pyrogenicity
- Stability testing
- Virology (in vitro, in vivo, specific virus testing)
- Process validation/viral clearance studies (including TSE)
Other
- Anti-venom potency testing
- Neurotoxin potency testing
- Custom method development
- Comprehensive molecular biology analysis
- Antisera development
To check which of our BPS facilities perform these services and get local facility contact information, click here. For additional information, contact us at askcharlesriver@crl.com.