Spinal Cord Injury Models
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Charles River Discovery Services' spinal cord injury (SCI) models apply NYU impactor or hemisection in order to induce functionally and histologically relevant injury. The ability to look at short-term histological changes as well as long-term and more comprehensive outcomes within an extensive functional battery offers powerful tools to evaluate elements of neuroprotection and neuroregeneration. All studies can be customized and adjusted as per client needs.
Models for Spinal Cord Injury
- Mild/Moderate T10 Contusion injury
- Severe T10 Contusion injury
- Hemisection model (unilateral injury)
Example Study Paradigm of Spinal Cord Injury Model
Click here to see a diagram outlining an example study paradigm using our Spinal Cord Injury model.
Data
BBB Score
Total Injury Volume of Spinal Cord Sections
For more information about our models used to research spinal cord injuries, please contact us at askcharlesriver@crl.com.
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spinal cord injury, SCI, spinal cord, NYU impactor, hemisection, neuroprotection, neuroregeneration, T10 Contusion, contusion, T10, BBB, locomotor test, inclined plane test, rotarod
Spinal Cord Injury Models | Charles River Discovery Services
Charles River Discovery Services' spinal cord injury (SCI) models apply NYU impactor or hemisection in order to induce functionally and histologically relevant injury.