Inflammation Models | Charles River Discovery Research Services

Thioglycollate-Induced Peritonitis (TIP) Model 

The accumulation of specific cell types at a site of injury is a characteristic of the inflammatory response. Charles River offers models to assess the recruitment of inflammatory cells to the site of sterile inflammation. Thioglycollate peritonitis permits the evaluation of cellular recruitment into the peritoneal cavity, while our sponge granuloma model captures infiltrating cells and their secreted products in subcutaneously implanted sterile PVA sponges. In each model, the composition of the elicited population is evaluated by flow cytometry.

Click here for Thioglycollate Peritonitis FACS data.

Chart of Total Peritoneal Cells from Saline and Thioglycollate Injected Mice

 

Total Peritoneal Cells from Saline and Thioglycollate Injected Mice

 

Chart of Differential Cell Counts from Thioglycollate-Induced Peritonitis

Differential Cell Counts from Thioglycollate-Induced Peritonitis

 


For more information about our Thioglycollate-Induced Peritonitis (TIP) model, please contact us at 1.877.CRIVER.1 or askcharlesriver@crl.com.

*Model under development
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