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phenotyping services
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We know that genetic manipulation in mice can present you with unique phenotypes. Charles River’s phenotyping screens offer a comprehensive, multi-step characterization of the anatomical, physiological, and behavioral changes in your newly created genetically engineered models.
The PhenoFirst® panel offers initial model characterization through the Primary Neurobehavioral Observation screen, designed as the first thorough look at your rat or mouse model, followed by therapeutic area-based phenotyping panels:
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Panels generally incorporate:
- In-life analysis with clinical examinations, primary behavioral observations, growth curves, reproductive analysis, and cognitive analysis
- Pathology services in support of phenotypic characterization with clinical pathology, necropsy evaluations, and histopathology
- Molecular phenotyping assays utilizing quantitative PCR (Q-PCR) techniques
- Biomarker screening via Multi-Analyte Profiles (MAP)
Charles River can breed and maintain your genetically engineered animal colonies and readily transfer the offspring to our phenotyping program. Alternatively, we can receive animals for phenotyping directly from your facility. |
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Phenotyping services, model characterization, phenotypic characterization, molecular phenotyping, biomarker screening, genetically engineered mouse models, in-life analysis, primary behavioral observations
Phenotyping Services | Phenotypic Characterization of Genetically Engineered Animal Models
Charles River’s phenotyping screens offer a comprehensive, multi-step characterization of the anatomical, physiological, and behavioral changes in your newly created genetically engineered animal models.