Charles River offers a wide range of study-specific analytical services by ELISA, EIA, Western blotting and HPLC.
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Western Blotting
- C99, C83 and holoAPP
- p-TAU / total Tau
- Synaptophysin
- NF-kappaB p65
- GLT-1 (GLAST)
- GAPDH
HPLC
- DA, DOPAC and HVA
- NA
- 5HT
- Glutamate
- Ach
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Protein expression and phosphorylation in tissue or cell culture samples can
be studied using Western blotting.

DAPT significantly decreases the soluble Aβ1-40 and Aβ1-42 levels in the hippocampus of Tg2576 mice.

Hippocampal Aβ1-40 in 5-Month-Old Tg2576 Mice

Hippocampal Aβ1-42 in 5-Month-Old Tg2576 Mice
Striatal dopamine level is significantly depleted in mice after MPTP-dosing.


For more information about our analytical services, please contact us at askcharlesriver@crl.com.