ORIGIN
Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1 mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.
COAT COLOR Hairless, albino background
RESEARCH APPLICATION
tumor biology and xenograft research
BREEDING LOCATION
Germany, Italy, UK, US, Canada
ADDITIONAL INFORMATION
For more information about CD-1 nude mice, please contact us at info@eu.crl.com.
Note: Heterozygous animals, which are not immunodeficient and have hair, are also available on request.