research animal models
SCID Hairless Congenic, SHC, SHC mouse, SHC mice, SCID, severe combined immunodeficiency, congenic, hairless mice, hairless mouse, hairless, immunodeficient, strain code 488, immunodeficient models, laboratory mice, lab mice, tumor biology, xenograft, H2d
SCID Hairless Congenic (SHC™) Mouse | Charles River
Charles River provides research animal models, including immunodeficient models such as the SCID Hairless Congenic (SHC™) mouse, for use in basic research and nonclinical drug discovery and development.
 overviewpricing & literature
 SCID Hairless Congenic (SHC™) MouseCB17.Cg-PrkdcscidHrhr/IcrCrl
ORIGIN
The hairless SCID congenic was created in 2009 by Charles River Research Models by using marker-assisted accelerated backcrossing to place the hairless gene (Hrhr) present in the Crl:SKH1-Hrhr stock onto a CB17/Icr-Prkdcscid/IcrIcoCr genetic background. These mice are homozygous for both Hrhr and Prkdcscid mutations, so exhibit the severe combined immunodeficiency phenotype characteristic of SCID mice and are also hairless.
COAT COLOR Hairless, albino background
RESEARCH APPLICATION
tumor biology and xenograft research
MHC HAPLOTYPE H2d
BREEDING LOCATION
US
ADDITIONAL INFORMATION
For more information about SCID Hairless Congenic (SHC™) mice, please contact us at info@eu.crl.com.
overviewpricing & literature
Informational Resources: SCID Hairless Congenic (SHC™) Mouse
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