Bioanalysis

The speed of lead candidate selection via rapid in vitro ADMET and pharmacokinetic screening is matched by an equally rapid analytical tool, Liquid Chromatography with Mass Spectrometry (LC/MS/MS). Charles River Laboratories offers non-GLP discovery bioanalytical services either in support of studies conducted in-house or as a stand-alone service, which can adapt to meet the rapid timelines and diverse needs required for the most efficient lead candidate selection. We currently serve the pharmaceutical, biotech, academic, government, and medical device markets, all to whom we offer a research grade assay approach via LC/MS/MS to quickly analyze samples for compound ranking. This research grade assay is a value-added service for our many other discovery offerings.

• Research grade assays
• Feasibility studies
• Metabolic profiling
• In vivo screening
• Rapid tissue analysis

Once a lead candidate has been selected in the discovery analytical process, these methods can be transferred to method development for GLP validation and preclinical and clinical sample analysis within Charles River.

What's New

Charles River and DSI to Co-Host Second Annual Safety Pharmacology Symposium and Workshop

Charles River Preclinical Services Announces Dates of 15th Annual Biotech Symposium

On-line Registration for the 2008 Charles River Short Course Now Available

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