Developmental and Reproductive Toxicology

Charles River Laboratories has been performing developmental and reproductive toxicity studies for pharmaceutical and biotechnology products for over 25 years. Using internationally-recognized guidelines, including International Conference of Harmonization (ICH) guidelines, we offer overall developmental and reproductive toxicology program planning and individual study design to conduct safety assessments for clients’ products. Since the emergence of the biotechnology industry in the mid-1980s, Charles River Laboratories has tested a broad range of biologics and can customize protocols to meet your individual requirements. 

Developmental and Reproductive Toxicology Services

• Routine toxicological evaluations
• Specialized neurobehavioral testing
• Assessments of growth (and the skeleton), pulmonary, and immunological development
• Toxicokinetic evaluations, including induction studies

Specialized Evaluation Techniques

• Hormone assays
• Male reproductive assessments (rodents and non-rodents)
• Variety of behavioral tests, including activity, learning, and memory, for prenatal and postnatal studies
• Range of developmental immunology tests that can be added to prenatal and postnatal studies
• Endocrine disrupter assessments (uterotrophic assay; Hershberger assay

What's New

Charles River and DSI to Co-Host Second Annual Safety Pharmacology Symposium and Workshop

Charles River Preclinical Services Announces Dates of 15th Annual Biotech Symposium

On-line Registration for the 2008 Charles River Short Course Now Available

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