Inhalation Toxicology

Utilizing knowledge from decades of experience in the field, Charles River offers a full range of inhalation toxicology study designs to support the worldwide registration of agrochemicals. 

In modern laboratory facilities, with custom-designed apparatus, we conduct a variety of study designs in multiple species.

Study Types

  • Acute toxicity
  • Subacute to chronic
  • Reproduction and teratogenicity
  • Neurotoxicology
  • ADME/TK
  • Dry powders
  • Aerosols
  • Emulsion sprays
  • Vapors
  • Gases
  • Compound-specific methodologies can be developed and validated
  • Sorbent tubes or impingers are used to sample test atmospheres
  • Chemical or gravimetric assessment of test atmospheres
  • Online infrared or GC analysis for gases and vapors
  • Real-time aerosol monitors (RAM-S) for measuring particulates
  • Aerosol particle size distribution monitored using cascade impactors or laser optical systems

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Toxicology

Leading the industry in the fields of reproductive toxicology, inhalation, infusion, bone research and other specialty toxicological assessments.

Ecotoxicology

Our custom-designed ecotoxicology facility is equipped to run aquatic and terrestrial ecotoxicology investigations.

Genetic Toxicology

Charles River has more than 25 years’ experience in the conduct of a wide range of genetic toxicology assays. We can assess the potential of your agrochemical product to induce genetic mutation or chromosomal damage.

Field Trials

Charles River runs field trials from GLP- and GEP-accredited field bases located throughout northern and southern Europe.