Toxicology

Charles River has been conducting toxicology studies for almost 50 years and offers the complete range of studies required for agrochemical product registration worldwide.

  • All routine routes of administration
  • Short-term and long-term (including carcinogenicity)
  • Single-dose acute (including oral, dermal, irritation and sensitization tests)
  • Immunotoxicology
  • Neurotoxicology
  • Endocrine disruptors

We also offer the full range of reproductive and developmental toxicity studies required for product registration.

  • Reproductive toxicology screening to OECD 421 and 422
  • Developmental toxicology in rats and rabbits
  • Multigenerational studies in rats

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Ecotoxicology

Our custom-designed ecotoxicology facility is equipped to run aquatic and terrestrial ecotoxicology investigations.

Physicochemical Characterization

We offer a full range of physicochemical testing to meet all regulatory requirements, either as full testing programs or stand-alone tests.

Genetic Toxicology

Charles River has more than 25 years’ experience in the conduct of a wide range of genetic toxicology assays. We can assess the potential of your agrochemical product to induce genetic mutation or chromosomal damage.